KANG Changming, et al. Correlation between oral glucose tolerance test and liver function in cirrhotic patients[J]. Journal of Chongqing Medical University, 2007,(6):657-658.
KANG Changming, et al. Correlation between oral glucose tolerance test and liver function in cirrhotic patients[J]. Journal of Chongqing Medical University, 2007,(6):657-658.DOI:
Objective:To investigate the correlation between the change of blood glucose and liver function after oral glucose tolerance test in cirrhotic patients.Methods:36 cirrhotic patients were classified into A
B and C groups according to Child-Pugh score.36 cirrhotic patients and 12 normal controls were given oral glucose tolerance test(OGTT)of 75g glucose after over night fasting.Venous blood samples OGTT 0
30
60
120 and 180 minutes were obtained.Results: The OGTT 60 and 120 minute’s blood glucose values in total cirrhotic group were significantly higher than that in the controls(P<0.005).And the OGTT 60 and 120 minute’s blood glucose values had an increasing tendency
as liver function got bad.The OGTT 120 minute’s blood glucose values had a significant correlation with ALB(r=-0.53
P<0.001).TBIL(r=0.43
P<0.001).prolonged PT(r=0.56
P<0.001).child-Pugh score(r=-0.54
P<0.001).Conclusion:The OGTT 120 minute’s blood glucose values had a significant correlation with liver function in cirrhotic patients.