Objectives:To study the roentgenographic signs of Hirschsprung’s disease (HD) proved by surgery and pathology in neonate.Methods:The roentgenographic manifestations and related X-ray signs of twenty cases in the nearest five years were retrospectively observed and analyzed. Results:(1) long-segment types accounted for 25% of all cases. (2) Intestinal motility abnormality

colonic obstruction and low small intestinal obstruction were the main manifestations of abdominal plain film

in which the former two accounted for 94%. Intestinal perforation was a relatively common complication (2cases).(3) Important signs of barium enema included local notch in the narrow rectum (12cases)

high tension sign (10cases) and spasm-and-contraction sign(12cases) in dilated loop

barium retention (13) and mixed barium-and-stool pattern (10) after 24 hours of follow-up. Conclusion:There is signifcantly difference between HD in neonatal and other period with regard to clinical feature

subtype profile and roentgenographic manifestation. It remains necessary to systemically research on the functional change of colon loop.