LUO Jia, et al. Determination of residual formamide in allopurinol by gas chromatography[J]. Journal of Chongqing Medical University, 2007,(11):1208-1209.
LUO Jia, et al. Determination of residual formamide in allopurinol by gas chromatography[J]. Journal of Chongqing Medical University, 2007,(11):1208-1209.DOI:
气相色谱法测定别嘌醇中甲酰胺残留
摘要
目的:建立别嘌醇中甲酰胺残留量气相色谱测定方法。方法:采用氢火焰离子化检测器(FID)
SUPLCOWAX-10柱分离。结果:甲酰胺在5~20μg/ml的浓度范围内呈良好的线性关系
平均回收率为95.57%(RSD=1.74%
n=6)。结论:本法适用于别嘌醇中甲酰胺残留量的测定。
Abstract
Objective:To establish method for determination of residual formamide in Allopurinol by gas chromato-graphy.Methods:Detected by FID detector
Separated by SUPLCOWAX-10.Results:The formamide show a good linear relationship at range of 5~20μg/ml
the average recovery was 95.57%.(RSD=1.74%
n=6)for formamide.Conclusion:It is quite suitable to be used in analysis of the formamide in Allopurinol.