Objective:To compare two type of anastomosis to institute vein graft model.Methods:Studies were performed by using normal New Zealand’s white rabbits(n=17

weight 2.0～2.5kg) which be divided into two group.Every rabbit’s unilateral jugular vein was anastomosed end-to-end with common carotid artery by interrupted suture(group A

n=9)or interrupted and continuous suture(group B

n=8).Samples of tissues were harvested after 1 mouth and examined under a light microscope.The vessel wall dimensions were measured by computer-aided planimentry.Results:The time of anastomosis and whole operation of group A are longer than group B(P<0.05).The bleeding of group A is more than Group B(P<0.05).All vien grafts are unobstructed and the total wall thickening.The neointimal and medial demostracted hyperplasia.But there is not statistically difference between the two goups.Conclusion:The method of anastomosis by interrupted and continuous suture is successfully and excelled that by single interrupted suture.