Objective:To explore the influence of background data in multinutrient treatment for neonate with infection pneumonia. To study the relative risk factors in VA nutritional state. Methods:the orally vitamin A and vitamin E

zinc

selenite daily in 111 neonates in the randomized

double-blind

placebo-controlled

clinical Trial for 7 days treatment. We investigated and analyze the relevant biochemical

immune evidence

clinic data and background data

with multivariate stepwise regression analysis. Results:Mother’s age

parity

gestation age and birth weight play positive influence to clinical restoring. Neonate’s age and birth weight play a positive role to serum IgM in early stage of pneumonia

but mother’ s age is negativity. Neonate’s age is positivity in enhancing serum VA

and is negativity in advancing serum IgM. Mother’s age play a negative role to heighten serum RBP. Conclusion:Mother’s age

parity

gestation age and neonate’s age is important factors to influence the clinical treatment effect. Great age and many parity mother’s neonate

earlier period and large for date infant are more possible to VAD during sick period

and are more slow to recover. So they need the nutritional intervention all the better.