ZHOU Kun, et al. Effect of ultrasound on early experimental osteoarthritis of rabbit knees[J]. Journal of Chongqing Medical University, 2008,(1):6-8.DOI:
Objective:To observe the effect of low intensity pulsed ultrasound on early experimental osteoarthritis of rabbit knees.Methods:Experimental osteoarthritis of rabbit knees were made by Hulth’s method.A total of 30 rabbits were divided averagely into 3 groups randomly.One hind knee of 10 rabbits of each group were treated with LIPU randomly while the others as control for 2、4 and 8 weeks respectively.All animals were sacrificed after LIPU.Then the histo-histochemical changes were evaluated by Mankin’s score method.Results:Mankin’s scores showed that the pathological changes in LIPU group were slighter than those in control group.Conclusion:LIPU can slow down the disease progress of experimental osteoarthritis of rabbit knee.