LI Bi-bo, et al. UV determination of content of sustained-release dropping pills of oleanolic acid and its dissolution rate[J]. Journal of Chongqing Medical University, 2009,34(4):447-451.
LI Bi-bo, et al. UV determination of content of sustained-release dropping pills of oleanolic acid and its dissolution rate[J]. Journal of Chongqing Medical University, 2009,34(4):447-451.DOI:
Objective:To establish UV method for the determination ofcontent of sustained-release droppingpills of oleanolic acid and its dissolution rate.Methods:In 207 nm wavelength
the content of sustained-release dropping pills of oleanolic acid and its dissolution rate were determinated by unico UV-2102PCS.Results:During the determination of the content
the calibration curves was linear in the concentration range of 20~80μg/ml
r=0.9995(n=7)
The recovery rate was 98.0%~102%
RSD<1%(n=3);during determining the dissolution rate
linearity was good within the concentration range of 10~70μg/ml
r=0.9997(n=7).The recovery rate was 98.0%~102%
RSD≤1%(n=3).Conclusion:The method is simple and rapid
and the results is accurate
reliable
and reproducible.It can be used to control the quality of sustained-release dropping pills of oleanolic acid with satisfactory results.