Objective:To evaluate the clinical effects of fasudil hydrochloride on patients with acute cerebral infarction. Methods:100 cases of acute cerebral infarction patients were randomly divided into treatment group(n=50) and control group (n=50). All the cases were given enteric-coated tablets aspirin

ligustrazine hydrochloride injection

piracetam and sodium chlorideand injection and mannitol injection

and so on. Additionally

in the treatment group fasudil hydrochloride injection 30 mg

dissolved in 100 ml 5% glucose or saline were injected intravenously. Results:Basic recovery rate and total effective rate of treatment control were significantly higher(P<0.01) than control group. Neurologic impairment score of treatment group significantly decreased(P<0.01) than pretherapy. Conclusion: Fasudil hydrochloride can effectively improve the clinical prognosis of patients with acute cerebral infarction

and may become a safe and effective drug in treating acute cerebral infarction .