Objective:To study the value of clinical application of 16-slice spiral CT in the diagnosis of acute chest pain.Methods:53 cases who presented with acute chest pain were included in the study.All of the patients underwent CTA examination to evaluate the coronary arteries

pulmonary arteries

thoracic and abdomen aorta.Coronary arteries angiography and interventional therapy was performed in 6 of the 53 cases.Multi-planar reconstruction(MPR)

maximum intensity projection(MIP)

curved-planar reconstruction(CPR)and volume rendering(VR)were used to display coronary arteries

pulmonary arteries

thoracic and abdomen aorta.The image quality was then evaluated according to whether the examinations can fulfill the clinical demand for the differential diagnosis of acute chest pain.Results:In the 53 cases

there were 33 cases with coronary arteries disease

9 cases with aortic dissection or dissecting aneurysm

2 cases with pulmonary arteries embolism

2 cases with spontaneous rupture of esophagus

2 cases with pneumothorax.Conclusion:CTA examination with 16-slice spiral CT can display the coronary arteries

pulmonary arteries

thoracic aorta in 11～13s with good image quality.It is of great value of clinical application in the etiological diagnosis for the patients with acute chest pain.