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重庆市合川区人民医院神经内科
纸质出版日期:2009,
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[1]汪毅.急性脑出血患者血清肌钙蛋白动态变化及临床意义[J].重庆医科大学学报,2009,34(07):971-973.
WANG Yi. Dynamic changes of plasma cardiac troponin-I and its clinical significance in patients with acute cerebral hemorrhage[J]. Journal of Chongqing Medical University, 2009,34(7):971-973.
目的:探讨急性脑出血(Acute cerebral hemorrhage
ACH)患者血清肌钙蛋白(Cardiac troponinⅠ
cTn-Ⅰ)含量动态变化及其对心肌损伤的诊断价值。方法:研究组ACH患者
检测98例ACH患者发病后<24h、72h、7d及14d时血清cTn-Ⅰ含量
入院时行神经功能缺损评分
并根据神经功能障碍程度分为轻、中、重3组;对照组检测98例健康体检者血清cTn-Ⅰ含量。结果:研究组在发病后24h、72h、7d时血清cTn-I含量与对照组和研究组发病14d时比较显著升高(P<0.01)
发病后14d血清cTn-Ⅰ含量与对照组比较差异无统计学意义(P>0.05);神经功能受损程度(National institutes of health stroke scale
NIHSS)评分越高
cTn-Ⅰ含量越高
3组cTn-Ⅰ含量在发病24h、72h、7d比较差异有统计学意义(P<0.05)。结论:急性脑出血早期血清cTn-Ⅰ含量明显升高
提示cTn-Ⅰ可作为早期检测急性脑出血患者心肌损害的一项指标。
Objective: discussion to the dynamic change of Serum cardiac troponin Ⅰ(cTn-Ⅰ) and the diagnostic value to the myocardial damage from patients with acute cerebral hemorrhage (ACH).Methods: study a group of 98 ACH patients; Serum cTn-I is measured in 98 patients with acute cerebral hemorrhage (ACH) at 24 h
72 h
7 d
14 d after the outbreak;Measure the nervous impairment when admission to hospital and divide it into mild
medium and heavy according to the dysfunction of nervous system;compare a group of 98 healthy physical testers and check their Serum cardiac troponin Ⅰ (cTn-Ⅰ) levels.Results: Serum cardiac troponin Ⅰ(cTn-Ⅰ) levels from 98 ACH patients at 24 h
72 h
7 d after the outbreak are distinctly higher than that from 98 ACH patients at 14 d and 98 healthy physical testers (P<0.01). The Serum cardiac troponin Ⅰ (cTn-Ⅰ) level from the group of 98 ACH patients at 14 d after the outbreak is meaningless in Statistics when compared (P>0.05);the higher the nervous impairment score in NIHSS is
the higher the cardiac troponin Ⅰ (cTn-Ⅰ) level is. The three cTn-I levels are distinctly meaningful when compared at 24 h
72 h
7 d after the outbreak(P<0.05).Conclusion: the early Serum cardiac troponin Ⅰ (cTn-Ⅰ) level of patients with acute cerebral hemorrhage (ACH) is obviously rising. So cTn-Ⅰ can be an index to the early investigation of myocardial damage from the patients with acute cerebral hemorrhage (ACH).
急性脑出血心肌损伤肌钙蛋白(IcTn-Ⅰ)
Acute cerebral hemorrhage (ACH)Myocardial damageCardiac troponin Ⅰ (cTn-Ⅰ)
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