Objective:To investigate the psychological health status and the intervention in patients with myocardial infarction. Methods:87 Patients with myocardial infarction were randomly divided into control group (n = 43) and psychological intervention group (n = 44). Both groups were assessed with Symptom checkist-90

Hamilton depression and behavior pattern test. The control group was treated with routine therapy. The psychological intervention group was treated with routine therapy

psychological intervention

and low dose fluoxetine hydrochloride. After three months of follow-up

New York Heart Association (NYHA) class

ejection fraction and the occurrence of adverse cardiac events were assessed. Results:The patients with myocardial infarction had high prevalence of psychological disorder (82.75%)

depression was the major symptoms (type-A behavior 62.07%). Compared with the control group

psychological disorder

NYHA class

and ejection fraction were significantly improved in the intervention group. Moreover

the occurrence of cardiac events was much lower than the control group. Conclusion:The patients with myocardial infarction had high prevalence of psychological disorder and the major symptoms were depression. The combination of routine therapy and psychological intervention may be effective at alleviation the symptoms and improvement the prognosis.