Objective:To investigate the feasibility and clinic effect of anesthesia with propofol-sufentanil in gastrofiberscopy in children.Methods:One hundred and twenty patients scheduled for elective gastrofiberscopy were randomized into two groups:group fentanyl(F) and group sufentani(lS)(n =60).group F were given intravenou midazolam 0.05 mg/kg

atropine 0.01 mg/kg

fentanyl 1 μg/kg

propofol 2 mg/kg

group S were given intravenou midazolam 0.05 mg/kg

atropine 0.01 mg/kg

sufentanil 0.01 μg/kg

propofol 2 mg/kg.The gas-trofiberscope was inserted after lash reflex had been extinct.Total dose of propofol

heart rate(HR)

mean arterial pressure(MAP)

pulse oxygen saturation(SPO2)

time of full recovery(answering correctly and walking without aid)

discomfort self-feeling were recorded and nausea and vomiting or dinus were noted.Results:At insertion of gastrofiberscope there was significant difference between MAP and HR in group F(P <0.05)

There was no significant difference in MAP and HR in group S(P >0.05).Compared with group F

there was sig-nificant difference in MAP

HR

SPO2 at insertion of gastrofiberscope in group S(P <0.05).Pain

dose of propofol

time of full recovery

discomfort self-feeling in group S were lower than those in group F.Conclusion:More stable HR and MAP lower respiratory depression

better recovery were achieved in children receving gastrofiberscopy with propofol-sufentanyl as anesthesis.