Objective:To investigate the clinicopathological features of malignant renal angiomyolipoma

to raise awareness of the disease.Methods:The malignant renal angiomyolipoma specimens collected by the pathology departments of the First Affiliated Hospital of Chongqing Medical University were analyzed.The specimens were under HE staining

light microscopy observation and immunohis tochemistry(SP method) staining.The information of clinical diagnosis and treatment were reviewed.Results:The characteristic histological patterns of the tumor was that epithelial cells

smooth muscle cells and fat cells appears in different proportion

thick-walled blood vessels could be seen

the mitosis was obvious

especially the pathological ones.Immunohistochemistry showed that epithelioid and smooth muscle cells characteristictly expresse HMB-45、EMA、Actin

and so on.Conclusion:B-ultrasonagraphy

CT

MRI is an important methods in the diagnosis of malignant renal angiomyolipoma

detailed family history and physical examination to be able to provide us with important clues to the diagnosis and pathological characteristics combined with immunohistochemistry is important in the final confirmation of the tumor.