Objective:To observe the anesthetic effects of SumianxinⅡ combined with diazepam on the Beagle dogs in experimental periodontal surgery to Provide the reference. Methods:Healthy adult male Beagle dogs were anesthetized with SumianxinⅡat the doses of 0.05、0.1、0.15 ml/kg in the combination group and diazepam(0.1 ml) by hip intramuscular injection simultaniously. Added injection dosage was half of the first dosage. Healthy adult Beagle dogs in the contral group were only anesthetized with SumianxinⅡ at the doses of 0.05、0.1、0.15 ml/kg by hip intramuscular injection. The time of adding anesthetic was not sure in surgery. Anesthesia induction period

initial duration of anesthesia

and adverse reactions after anesthesia were compared between the two groups. Results: The combined treatment group induction dose respectively (11.00±1.41) min

(9.00±0.82) min

(12.75±0.50) min

For the first time maintaining anesthesia(29.75±6.62) min

(46.00±5.29) min

(45.25±6.02) min

Intraoperative additional one times longer cansustain anesthesia for(38.75±3.50) min

(45.25±4.03) min

(37.25±2.75) min. Pure Sumianxin Ⅱ new standards of sleep narcotic induction respectively respectively was (15.75±2.50) min

(14.25±2.99) min

(14.50±2.08) min

For the first time maintaining anesthesia was (20.75±5.19) min

(20.5±3.42) min

(22.25±5.19) min

the time of adding anesthetic was not sure in surgery. 2 Dogs died in SumianxinⅡ group. United drug group simple Sumianxin Ⅱ induction period in each group by t test

Sumianxin Ⅱat the doses of 0.1 ml/kg supplemented with 0.3 ml dose stability (P<0.05). Combined treatment group and simple Sumianxin Ⅱ initial maintenance of anesthesia time by t test (P<0.05).Conclusion: Sumianxin Ⅱ at the dose of 0.1 ml/kg joint stability 0.3 ml dose of anesthesia when synergies good

anesthetic effect than alone Sumianxin Ⅱ more satisfied

Postoperative awakening

high reliability and less adverse reactions after anesthesia

in favor of the experiment for longer periods of time Beagle dog-week experimental surgery.