n-HA/PA66人工椎体在颈椎病中的临床应用

张荣; 权正学; 蒋电明; 欧云生; 唐可; 李基明

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n-HA/PA66人工椎体在颈椎病中的临床应用

临床研究 | 更新时间：2024-01-17

- n-HA/PA66人工椎体在颈椎病中的临床应用
- Application of nano-hydroapatic crystals and polymide compsite for artificial vertebrae in anterior cervical fusion of cervical spondylosis
- 重庆医科大学学报 2009年34卷第11期页码：1562-1565
- 作者机构：
  
  重庆医科大学附属第一医院骨科
- 作者简介：
- 基金信息：
  
  国家科技支撑计划“活性纳米复合生物材料制品应用开发”（编号:2007BAE13B04）;重庆市科委课题资助（编号:CSTC2007BB5265）
- DOI：
  中图分类号： R687.3
- 纸质出版日期：2009，
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[1]张荣,权正学,蒋电明,欧云生,唐可,李基明.n-HA/PA66人工椎体在颈椎病中的临床应用[J].重庆医科大学学报,2009,34(11):1562-1565.

ZHANG Rong, et al. Application of nano-hydroapatic crystals and polymide compsite for artificial vertebrae in anterior cervical fusion of cervical spondylosis[J]. Journal of Chongqing Medical University, 2009,34(11):1562-1565.
[1]张荣,权正学,蒋电明,欧云生,唐可,李基明.n-HA/PA66人工椎体在颈椎病中的临床应用[J].重庆医科大学学报,2009,34(11):1562-1565. DOI：

ZHANG Rong, et al. Application of nano-hydroapatic crystals and polymide compsite for artificial vertebrae in anterior cervical fusion of cervical spondylosis[J]. Journal of Chongqing Medical University, 2009,34(11):1562-1565. DOI：

摘要

目的:探讨用n-HA/PA66人工椎体治疗颈椎病的临床疗效。方法:2005年2月至2008年3月

我科对53例颈椎病患者

行颈前路椎体次全切除n-HA/PA66人工椎体植入钛板内固定术。术后观察患者脊髓功能恢复情况

颈椎曲度、椎间隙高度变化情况

植骨融合情况

并发症、切口愈合情况。通过与同期在我科行钛网植骨融合的颈椎病患者对照

评估其临床效果。结果:全部患者均获门诊或电话随访。两组所有患者术后较术前脊髓功能、颈椎曲度、椎间隙高度改善明显

植骨融合率100%。n-HA/PA66人工椎体组术中术后未见并发症

钛网组有5例术后出现钛网下沉。两组比较

n-HA/PA66人工椎体组在脊髓功能、颈椎曲度、椎间隙高度、植骨融合率及局部反应等方面与钛网组无明显差异;在术后并发症方面优于钛网组。结论:n-HA/PA66人工椎体能有效恢复颈椎曲度及椎间隙高度;植骨融合率高。应用于颈前路治疗颈椎病的手术中可获得满意的临床疗效。

Abstract

Objective:To evaluate the effect of artificial vertebral body of the biomimetic n-HA/PA66 composites in the anterior cervical fusion for cervical spondylosis.Methods: From December of 2003 to May of 2008

53 patients with cervical spondylosis were treated by anterior semivertebra decompression

intervertebral fusion with artificial vertebral body of the biomimetic n-HA/PA66(HG)composites

fixation with titanium plate.The patients were followed-up.Nerve functional restoration

D numerieal value

intervertebral space

fusion rate of the bone graft

local response

and complication postopenative were all observed.Compared with the patients treated by bone graft and interbody fusion with titanium(TG)

the efficacy of the present tool was evaluated.Results: All patients were followed up by clinic service or telephone.The effects were conspicuous in recovering the spinal cord

D numerieal value

and intervertebral space.Fusion rate of the bone graft

local response was 100%.No complications was found.The HG was the same with the TG in improvement of the spinal cord function

D numerieal value

intervertebral space

fusion rate of the bone graft

and local response.The HG presented better results than the TG in occurrence of complication.Conclusion: Artificial vertebral body of the biomimetic n-HA/PA66 composites can recover cervical vertebra curvature and intervertebral heights

with high rate of bone graft fusion and firm fixation.

关键词

颈椎病脊柱重建术羟基磷灰石

Keywords

cervical spondylosisSpine reconstructionydroxyapatite

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