Objective:To identify the safety and efficiency of polymer clip (Hem-o-lok) for routine control of renal artery and vein during retroperitoneal laparoscopic nephrectomy (RLPN). Methods: From June 2007 to June 2009

34 patients underwent RLPN

Of which 21 cases of renal cell carcinoma

5 cases of renal pelvis/ureter cancer

3 cases of non-functioning kidney and renal atrophy

5 cases of renal tuberculosis. Renal arterial and venous control were achieved solely by the Hem-o-lok clips where at least two clips were applied on the patient side. Results: 31 cases of RLPN were successful

because 2 cases due to severe adhesions and bleeding

1 case due to equipment failure during laparoscopic procedure

diverted open nephrectomy. Renal arterial and venous control using the Hem-o-lok clips were successful without any slipping of clips or uncontrolled bleeding. The mean Operating time was 100 minutes (60~150 minutes)

the mean blood loss was 90 ml (50~200 ml) without blood transfusion. Follow-up was carried out for 1-24 months

no recurrence found in any patients with renal tumor or ureter tumor; 5 cases of renal tuberculosis recovered smoothly by further anti-tuberculosis treatment; one patient suffered from serious retroperitoneal inflammation

recovered smoothly after close anti-sepsis; a sense of wound pain

numbness in 3 patients

disappeared after 6 months. Conclusion: The Hem-o-lok clip is a safe

convenient and economical device for vascular control in RLPN. RLPN with minimal invasion is expected to become the first choice for nephrectomy.