围手术期疼痛与绝经期妇女血管内皮功能关系的研究

伍孟军; 魏安宁; 胡艳君; 续平; 胡锦生; 昝利萍; 江燕; 张航

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围手术期疼痛与绝经期妇女血管内皮功能关系的研究

临床研究 | 更新时间：2024-01-17

- 围手术期疼痛与绝经期妇女血管内皮功能关系的研究
- A study for the relationship between pain and arterial endothelium function in menopause women during preoperation
- 重庆医科大学学报 2009年34卷第10期页码：1400-1403
- 作者机构：
  
  1. 重庆医科大学附属第二医院麻醉科
  2. 香港中文大学内科与药物治疗系
  3. 重庆医科大学附属第一医院内分泌科
- 作者简介：
- 基金信息：
- DOI：
  中图分类号： R543
- 纸质出版日期：2009，
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[1]伍孟军,魏安宁,胡艳君,续平,胡锦生,昝利萍,江燕,张航.围手术期疼痛与绝经期妇女血管内皮功能关系的研究[J].重庆医科大学学报,2009,34(10):1400-1403.

WU Meng-jun, et al. A study for the relationship between pain and arterial endothelium function in menopause women during preoperation[J]. Journal of Chongqing Medical University, 2009,34(10):1400-1403.
[1]伍孟军,魏安宁,胡艳君,续平,胡锦生,昝利萍,江燕,张航.围手术期疼痛与绝经期妇女血管内皮功能关系的研究[J].重庆医科大学学报,2009,34(10):1400-1403. DOI：

WU Meng-jun, et al. A study for the relationship between pain and arterial endothelium function in menopause women during preoperation[J]. Journal of Chongqing Medical University, 2009,34(10):1400-1403. DOI：

摘要

目的:通过颈动脉内-中膜厚度（Intima-mediathickness

IMT）和肱动脉内皮依赖性扩张功能（Endothelium-dependent dilation

EDD）的检测

探讨围手术期疼痛与绝经期妇女血管内皮功能的关系。方法:采用B型超声检测围手术期绝经期女性上腹手术患者30名

测定手术前与手术后颈动脉内-中膜厚度和肱动脉内皮依赖性扩张功能;手术前后疼痛视觉模拟评分。结果:围手术期

绝经期女性颈动脉内-中膜平均厚度（0.78±0.37）mm;麻醉苏醒后（意识指令性恢复

自动性睁眼

抬头>5 s）2 h肱动脉内皮依赖性扩张功能为5.2%±1.0%

较手术前6.2%±1.5%有统计学差异（P<0.05）;麻醉苏醒后2 h疼痛视觉模拟评分4.9±2.7较手术前1.03±1.9有统计学差异（P<0.001）

且肱动脉内皮依赖性扩张功能的改变与疼痛刺激有独立相关性（r=0.868

P=0.032）。结论:围手术期手术疼痛与绝经期女性的血管内皮功能的降低有密切关系。

Abstract

Objective: To investigate the intima-media thickness(IMT) of carotid artery and endothelium-dependent dilation(EDD)

and evaluate the relationship between pain and arterial endothelium function on menopause women during preopertion.Methods: The IMT and EDD in 30 menopause women were measuring by using B-mode ultrasound

pre-operatively and post-operatively;The visual analogue score(VSA) were mead pre-operatively and post-operatively.Results:IMT on carotid artery was(0.78±0.37)mm;EDD(5.2%±1.0%) at 2 hour after recovery from anesthesia was significantly lower than pre-operative EDD(6.2%±1.5%)(P<0.05).VSA(4.9±2.7) at 2 hour after recovery from anesthesia was significantly lower than pre-operative VSA(1.03±1.9)(P<0.001).Dependent relations existed between EDD and pains(r=0.868

P=0.032).Conclusion: This is significant relationship between pain and arterial endothelium function in menopause women during preopertion.

关键词

B型超声颈动脉内-中膜厚度肱动脉内皮依赖性扩张功能疼痛绝经期女性

Keywords

B-mode ultrasoundIntima-media thickness(IMT)Endothelium-dependent dilation(EDD)painMenopause women

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