LI Sheng, et al. Rapid establishment of rabbit model of mammary dysplasia and its estrogen receptor alpha distribution[J]. Journal of Chongqing Medical University, 2009,34(11):1534-1537.
LI Sheng, et al. Rapid establishment of rabbit model of mammary dysplasia and its estrogen receptor alpha distribution[J]. Journal of Chongqing Medical University, 2009,34(11):1534-1537.DOI:
Objective:To investigate the feasibility of rapidly making rabbit model of mammary hyperplasia.Methods:Estradiol benzoate and Progesterone were given intramuscularly to New Zealand white rabbits during different periods.The preparation of the model
its available time
pathological type and estrogen receptor alpha distribution were observed.Results:After 20~25 days
the models were estabished
which fulfilled the features of mammary dysplasia
making ovariectomy unnecessary.The model could be maintained for 135 days.Conclusion:The model has the same pathological feature with human.Rapid modeling is feasible