Objective：To explore the effect of health education pathway on the health knowledge，health belief and self-management in patients with coronary stent implantation. Methods：One hundred and twenty patients with coronary artery disease who were going to receive stent implantation in the department of cardiology of our hospital were selected by convenient sampling，and they were divided into the intervention group and the control group randomly. For patients in the intervention group，health education pathway was used to give health education to them，and for patients in the control group，they received routine health education. Then their health knowl－edge，health beliefs at admission and discharge，as well as the self-management behavior scores at three months after discharge in the two groups were compared. Results：At the day of discharge，the knowledge，belief scores in the intervention group were （55.77±7.71），（18.90±2.06），which were higher than （43.93±9.65），（16.40±2.85） in the control group，and the differences were statistically sig－nificant（P<0.001）. The mode and time of health education had interactive effect on the scores of health knowledge and health belief in patients. At three months after discharge，scores of self-management behaviors in the intervention group was （100.73±8.68），which was higher than （91.13±10.70） in the control group，and the differences were statistically significant（t=5.197，P=0.000）. Conclusion：Health education pathway can improve the knowledge，belief level and self-management behavior of patients with coronary stent implantation.