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1. 重庆医科大学附属第一医院 1. 放射科
2. 血管外科,重庆,400016
纸质出版日期:2019,
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魏淼, 李信友, 赵渝, 等. 单色能量CTA成像结合锐利迭代重建技术评价支架术后再狭窄的效果[J]. 重庆医科大学学报, 2019,44(10):1332.
Wei Miao, Li Xinyou, Zhao Yu, et al. Application of CTA with monoenergetic imaging combined with iterative reconstruction using a sharp convolution kernel in the evaluation of in-stent restenosis[J]. Journal of Chongqing Medical University, 2019,44(10):1332.
魏淼, 李信友, 赵渝, 等. 单色能量CTA成像结合锐利迭代重建技术评价支架术后再狭窄的效果[J]. 重庆医科大学学报, 2019,44(10):1332. DOI:
Wei Miao, Li Xinyou, Zhao Yu, et al. Application of CTA with monoenergetic imaging combined with iterative reconstruction using a sharp convolution kernel in the evaluation of in-stent restenosis[J]. Journal of Chongqing Medical University, 2019,44(10):1332. DOI:
目的:研究下肢CTA单色能量成像结合中等锐利迭代重建(B60f,SAFIRE)技术在下肢血管支架植入术后再狭窄(in-stent restenosis,ISR)诊断中的应用价值。方法:对72例(男37,女35)股动脉植入支架的患者行下肢动脉CT血管造影(comput-er tomography angiography,CTA)。25例采用双能量扫描,中等锐利迭代重建(B60f SAFIRE),分离出2组(70 keV锐,80 keV锐)单色能量图像。47例采用100 kV扫描,其中23例(100 kV标组)标准平滑迭代重建(50% ASIR),24例(100 kV锐组)中等锐利迭代重建(B60f SAFIRE)。比较图像噪声(SD)、信噪比(SNR)、对比噪声比(CNR)、支架-血管密度差(SVD)、测量-实际支架壁厚差(MAD),结合血管超声或DSA,评价ISR的诊断准确率。结果:①不同重建同能级:SD,100 kV标<100 kV锐,SNR、CNR之间无统计学差异(P>0.05)。②不同能级同重建比较:SD,70 keV锐<80 keV锐<100 kV锐,各组间差异有统计学意义(P<0.05)。腔内SNR和CNR:100 kV锐<70 keV锐<80 keV锐,组间差异有统计学意义(P<0.05)。③支架-血管密度差(SVD):70 keV锐<80 keV锐<100 kV锐<100 kV标,测量-真实支架壁厚差(MAD):80 keV锐<100 kV锐<70 keV锐<100 kV标,组间差异有统计学意义(P<0.05)。④主观图像质量评分:70 keV锐<100 kV标<100 kV锐<80 keV锐(P<0.05),支架内再狭窄的诊断准确率:70 keV锐(71.04%)<100 kV标(86.19%)<100 kV锐(91.27%)<80 keV锐(95.8%),(χ2=9.95,P=0.019),?资=0.743(P<0.05)。结论:80 keV锐单色能量结合中等锐利迭代重建(B60f SAFIRE)成像有助于优化支架血管CTA的图像质量,提高ISR的诊断准确率。
Objective:To study the practical value of computed tomography angiography(CTA) with monoenergetic imaging combined with iterative reconstruction using a medium-sharp convolution kernel(B60f,SAFIRE) in the diagnosis of in-stent restenosis(ISR) of the lower extremities. Methods:CTA of the lower extremity arteries was performed in 72 patients(37 males and 35 females) with a stent implanted in the femoral artery. Among the above patients,25 underwent dual-energy scanning combined with iterative recon-struction using a medium-sharp convolution kernel(B60f,SAFIRE) and were subdivided into two monoenergetic imaging groups(70 keVsharp and 80 keVsharp);47 underwent 100-kV scanning and were subdivided into 100 kVstandard group(23 cases,using adaptive statistical iterative reconstruction[50% ASIR]) and 100 kVsharp group(24 cases,using iterative reconstruction with a medium-sharp convolution kernel[B60f,SAFIRE]). These groups were com-pared for image noise(standard deviation[SD]),signal-to-noise ratio(SNR),contrast-to-noise ratio(CNR),stent-vessel deviation(SVD),and measured-actual deviation(MAD);the diagnostic accuracy for ISR was evaluated by taking into ac-count the results of vascular ultrasound or digital subtraction angiography. Results:In groups of the same energy level and processed with different reconstruction methods,the image noise(SD) was significantly lower in the 100 kVstandard group than in the 100 kVsharp group;there were no significant differences between groups in SNR or CNR(P>0.05). Between groups of different energy levels and processed with the same reconstruction method,there were significant differences in image noise(SD)(70 keVsharp<80 keVsharp<100 kVsharp,P<0.05) and intraluminal SNR and CNR(100 kV sharp<70 keVsharp<80 keVsharp,P<0.05). There were significant differences between groups in SVD(70 keVsharp<80 keVsharp<100 kVsharp<100 kVstandard,P<0.05),MAD(80 keVsharp<100 kVsharp<70 keVsharp<100 kVstandard,P<0.05),subjective image quality score(70 keVsharp<100 kVs-tandard<100 kVsharp<80 keVsharp,P<0.05),and diagnostic accuracy for ISR(70 keVsharp(71.04%)<100 kVstandard(86.19%)<100 kVsharp(91.27%)<80 keVsharp(95.8%),( χ2=9.95,P=0.019),κ=0.743,P<0.05). Conclusion:Monoenergetic imaging combined with iterative reconstruc-tion using a medium-sharp convolution kernel(B60f,SAFIRE) in the 80 keVsharp group can help optimize the image quality of CTA for stent-implanted vessels and improve the diagnostic accuracy for ISR.
单色能量成像锐利卷积核迭代重建支架术后再狭窄
monoenergetic imagingiterative reconstruction using a medium-sharp convolution kernelin-stent restenosis
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