objective To investigate the willingness to accept PrEP and its influencing factors among regular sex partners of HIV-infected individuals in Sichuan and Xinjiang province . Methods Face-to-face anonymous questionnaire was conducted to 473 qualified objects by non-randomly sampling method. test was employed to conduct univariate analysis

multivariate analysis was conducted using logistic regression .Results Awareness of PrEP among PAR was not high in Sichuan and Xinjiang province

85.41% had never heard of PrEP

but reached to 80.34% after being taught on PrEP related knowledges by investigators. Logistic regression showed that the multiple influencing factors of the willingness to accept PrEP among PAR population were nation (Uyghur / Han:OR=2.471

P=0.0093)

monthly income levels(<= 1000/1001-3000: OR = 2.046

P =0.0184)

whether have sex with spouse within six months (yes / no: OR = 2.263

P = 0.0192)

self-awareness of the possibility to be infected with HIV from their spouses (medium possibility/great: OR=0.485

P=0.0651；low possibility/great:OR=0.447

P=0.0273)

whether would recommend friends to use PrEP (would / would not: OR = 9.416

P