Objective：To investigate the clinical application value of ureteroscope pneumatic lithotripsy（URSL） with NGage extraction basket in the treatment of upper ureteral calculi. Methods：Totally 129 patients with upper ureteral calculi were randomly divided into two groups，73 patients in control group were treated by URSL，56 patients in Ngage group were treated by URSL combined with NGage. Results：Sixty patients were treated and placed double J（D-J） stents successfully in control group，with the success rate of primary lithotripsy being 82.19%；12 patients had residual fragments after operation. Fifteen-three patients were treated and placed D-J stents successfully in NGage group with the success rate of primary lithotripsy in NGage group being 94.64%，higher than that of control group（ ?字2=4.522，P=0.033）；residual calculi was not found at 4-8 weeks after operation by plain film of kidney ureter and bladder. Rate of residual calculi in NGage group was significantly lower than that in control group（ ?字2=10.150，P=0.001）. There was no significant difference between two groups in the operation time（t=1.847，P=0.067），complication rate（ ?字2=0.000，P=1.000） and hos－pitalization time（t=0.331，P=0.741）. Conclusions：URSL with NGage extraction basket can efficaciously prevent calculi from moving upward in the treatment of upper ureteral calculi，which can achieve higher success rate and lower residual calculi rate.