Objective：To analyze the efficacy of posterior decompression，fusion，pedicle screw system fixation in the treatment of de－generative lumbar scoliosis with stenosis（DLSS）. Methods：Thirty-three patients with DLSS in our hospital from July 2008 to June 2011 were analyzed retrospectively，including 11 males and 22 females. All the patients were underwent posterior decompression，fusion，pedicle screw system fixation. Visual analog symptom rating scale（VAS），Oswestry disability index（ODI） and the Cobb angle on the lumbar coronal film were used for efficacy assessment. Results：All patients were followed up for 12-26 months，averaged（17.27±3.78） months. Mean preoperative VAS score，ODI score and Cobb angle were （7.00±0.90） points，（70.61±7.29）% and （20.58±9.96） degrees while those at the last follow-up were （3.00±0.97） points，（31.42±9.22）% and （6.12±3.22） degrees，with significant differences between preoperative and postoperative results（P<0.05）. Excellent rate of ODI was 72.73%. During the follow-up，the height of disc space was remained，fusion cage were not displaced，no case of internal fixations breakage was observed and rate of fusion for bone graft was 100%. Conclusions：Posterior decompression，fusion，pedicle screw system fixation is an effective surgical treatment for DLSS.