Objective：To explore the treatment for complications after percutaneous renal biopsy in children and to summarize nursing experiences in order to provide references for pediatric clinical work. Methods：Clinical data of 2 160 children receiving renal biopsy in our hospital from January 1999 to December 2012 were retrospectively analyzed including related complications and treatment and nursing care methods. Results：There were 1 728 cases（80%） of gross hematuria，367 cases（17%） of perirenal hematoma，216 cases （10%） of back pain，43 cases（2%） of urinary retention，2 cases（0.1%） of renal artery pseudoaneurysm and there was no other organ damage or death. Conclusion：The development and promotion of renal biopsy helps to improve the diagnosis and treatment of child renal disease and promote the development of pediatric nephrology. Scientific treatment and nursing intervention can effectively reduce the incidences of hematuria，hematoma and other complications and improve the poor prognosis.