Objective：To explore risk factors of frequent atrial premature beats（FAPBs） and atrial tachycardia（AT）. Methods：Case-control study was conduced to check Holter reports of patients in the First Affiliated Hospital of Chongqing Medical University during July 2011 to June 2012. Totally 478 patients were enrolled including 230 patients with FAPBs and 248 patients with sporadic atrial premature beats（SAPBs） or putting another way，147 patients with AT and 61 patients with atrial premature beats（APBs）. Dif－ferences in constituent ratio among different factors between FAPBs and SAPBs were compared. The above statistically sig－nificant factors of FAPBs relative to SAPBs were analyzed by logistic regression and risk factors of AT relative to APBs were analyzed by the same way. Results：Age（OR=1.018，P=0.049），history of hypertension（OR=1.653，P=0.035） and heart function（OR=1.421，P=0.006） were potential risk factors of FAPBs relative to SAPBs. Age（OR=1.060，P=0.000） and valvular heart disease（OR=1.584，P=0.012） may be risk factors of AT relative to APBs. Conclusion：Early prevention and treatment of hypertension and valve lesions is likely to reduce the incidence of FAPBs and AT. Elderly FAPBs and AT patients needn’t be intervened actively.