Objective：To explore the application of Vidatak EZ communication board in acute exacerbation in chronic obstructive pul－monary disease（AECOPD） patients who received invasive mechanical ventilation. Methods：Totally 131 patients who admitted into respiratory ICU of our hospital from October 2011 to November 2012 were enrolled in the study. They were randomly divided into two groups：experimental group（n=65） and control group（n=66）.Vidatak EZ board was used to communicate with patients in experimental group while text card was used to communicate with patients in control group. General condition of the two groups were recorded. In－cidence of ICU delirium in two groups were assessed by confusion assessment method for ICU. Mechanical ventilation duration，ICU duration and total hospital duration，treatment outcome and incidence of ICU delirium were compared between the two groups. Results：No statistical difference was noted in general condition，acute physiology and chronic health evaluationⅡ，ICU duration，total hospital duration and treatment outcome between two groups（all P >0.05）. Duration of mechanical ventilation was less in experimental group than in control group with statistically differences（P<0.05）. Incidence of ICU delirium was lower in experimental group than in con－trol group with statistically differences（P<0.05）. Conclusion：Vidatak EZ communication board can effectively shorten the duration of mechanical ventilation and reduce the incidence of ICU delirium in AECOPD patients who received invasive mechanical ventila－tion，therefore it has good application prospect.