Zhong Jianjun, Sun Xiaochuan. Recent advances in the function of aquaporin-4 in central nervous system[J]. Journal of Chongqing Medical University, 2014,38(4):421-425.
Zhong Jianjun, Sun Xiaochuan. Recent advances in the function of aquaporin-4 in central nervous system[J]. Journal of Chongqing Medical University, 2014,38(4):421-425.DOI:
Aquaporin-4(AQP-4) is the most abundant aquaporin in central nervous system(CNS). Water movement cross cell mem-brane is mainly conducted by AQP-4. Previous studies of AQP-4 mainly focused on edema formation after various brain injuries,but recently AQP-4 has been found to connect with many other brain functions and diseases,such as regeneration and inflammation. Therefore,these researches were reviewed to renew current views on AQP-4 in CNS,hoping to provide new threads for the exploration of drugs against AQP-4.