Objective：To explore the feasibility of low power focused ultrasound in the treatment of hyperplasia of mammary glands. Methods：Twenty-one patients diagnosed as hyperplasia of mammary glands accepted low power focused ultrasound treatment，and re－ceived examination of breast ultrasonography or mammography. All patients were followed up separately for 1，3，6，12 months after the treatment. Results：Pain score of twenty-one patients was collected at 1，3，6，12 months after treatment. There were statistical differ－ences in pain score before and after the treatment（F=133.45，P=0.00）. There was no statistical difference in thickness of hyperplasia gland between one month after the treatment and before the treatment（P=0.06） due to short time of follow-up. There were statistical differences in thickness of hyperplasia gland between 3，6，12 months after the treatment and before the treatment（F=10.9，P=0.00）. Da－ta system grading of breast image reports decline in 13 patients（13-21，62%）. Conclusion：It is effective to treat hyperplasia of mam－mary gland with low power focused ultrasound.