Objective：To observe the adverse effects of Chinese-moxibustion treatment and the effect of optimized nursing process on minimizing the adverse effects. Methods：After reasons of adverse effects in Chinese-moxibustion being analyzed and nursing process optimized with flowchat，the execution power of nurses and the awareness in patients of adverse effects were observed. Then，the inci－dences of adverse effects in Chinese-moxibustion treatment were compared before and after optimized nursing process. Results：The execution power of nurses and the awareness rate of patients and their families on Chinese-moxibustion treatment were both increased significantly with optimized nursing process. Incidence of adverse effects in Chinese-moxibustion treatment with optimezed nursing process in 2012 was descended significantly than that without optimized nursing process in 2011. Conclusion：Optimized nursing pro－cess in Chinese-moxibustion treatment can reduce the adverse effects occurrences，and also improve the treatment effect in order to enhance the compliance and satisfaction of patients on Chinese-moxibustion treatment.