Objective：To analyze the CT manifestation of hepatic lesions with obvious enhancement in arterial phase and to summarize its characteristics. Methods：CT manifestations of 80 cases of hepatic lesions with obvious enhancement in arterial phase were retro－spectively analyzed；all cases were confirmed by operation and pathology. Results：The majority of lesions enhanced in the arterial phase displayed following characteristics：the central scar in focal nodular hyperplasia（FNH），hepatocellular carcinoma and hepatic hemangioma，calcification in fibrolamellar hepatocellular carcinoma，dynamic enhancement pattern of “fast in fast out” in heteroge－neous enhancement of liver cancer，enhancement pattern of “fast in slow out” in hemangioma，“bull eye sign” in liver metastases. Ac－curate diagnosis for most cases can be made based on these characteristics along with other CT manifestations. Conclusion：Character－istics of hepatic lesions with obvious enhancement in arterial phase along with other CT manifestations are of great value in diagnosis and differential diagnosis of the lesions.