Objective：To investigate the correlation between intraoperative complications during interventional therapy in children with congenital heart diseases and anesthesia management safety and to put forward corresponding preventive measures. Methods：A retro－spective analysis was made on type，incidence，cause and treatment of adverse events after undergoing different anesthesia treatments （intravenous anesthesia，laryngeal mask combined with intravenous inhalation anesthesia and tracheal intubation） in 1 792 cases of interventional therapy. Results：Incidence of adverse event related with anesthesia was 3.63%（65/1 792）. After timely treatment，all recovered well. Incidence of adverse event related with operation was 2.40%（43/1 792），including 4 death cases died with mortality of 0.22%（4/1792）. The intravenous anesthesia group had the highest incidence of adverse events（12.6%，P=0.000）. Conclusion：Choosing appropriate anesthesia methods based on patients’ different physical condition can strengthen management of high risk fac－tors and formulate appropriate urgent treatment plan. Effective peri-operative monitoring and effective cooperation can reduce the in－cidence of serious complications in children’s congenital heart disease intervention.