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1. 重庆市中医院放射科,重庆,400021
2. 重庆医科大学附属大学城医院,重庆,401331
3. 重庆市中医院药剂科,重庆,400021
纸质出版日期:2018,
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王军大, 崔渺, 李艳艳, 等. MRI钆剂瘘管造影与DCE-MRI联合使用对高位复杂型肛瘘细小分支瘘管及瘘口的诊断价值[J]. 重庆医科大学学报, 2018,43(1):60.
Wang Junda, Cui Miao, Li Yanyan, et al. Value of MRI Ga fistulography combined with DCE-MRI in the diagnosis of high complex anal fistula with small branch fistula and orificium fistulae[J]. Journal of Chongqing Medical University, 2018,43(1):60.
王军大, 崔渺, 李艳艳, 等. MRI钆剂瘘管造影与DCE-MRI联合使用对高位复杂型肛瘘细小分支瘘管及瘘口的诊断价值[J]. 重庆医科大学学报, 2018,43(1):60. DOI:
Wang Junda, Cui Miao, Li Yanyan, et al. Value of MRI Ga fistulography combined with DCE-MRI in the diagnosis of high complex anal fistula with small branch fistula and orificium fistulae[J]. Journal of Chongqing Medical University, 2018,43(1):60. DOI:
目的:MRI钆剂瘘管造影与动态对比增强磁共振成像(dynamic contrast enhanced MRI,DCE-MRI)联合使用,对高位复杂型肛瘘进行诊断,探讨其对高位复杂型肛瘘术前评估的指导意义。方法:收集2014年12月10日至2016年12月10日MRI平扫初步证实为高位复杂型肛瘘但细小内瘘口、分支瘘管显示不清的患者264例,首先行DCE-MRI检查,30 min后再行瘘管内注入钆特酸葡胺4 mL+生理盐水16 mL造影检查同步DCE-MRI扫描。分别对MRI平扫、DCE-MRI及瘘管造影+DCE-MRI诊断结果特异度及敏感度行约登指数、ROC曲线下面积(AUC)进行检验。结果:瘘管造影+DCE-MRI示高位复杂型肛瘘外瘘口、内瘘口及分支瘘管显示清晰,瘘管T1WI、T2WI上呈高信号;脓肿为不规则形或马蹄状,T1WI等、稍低信号,T2WI、脂肪抑制高信号。对照手术结果,瘘管造影+DCE-MRI对于术前诊断对于细小内瘘口及细小分支瘘管的诊断价值明显提高;MRI平扫对于细小瘘管显示约登指数为31.60%,曲线形面积为0.576,对于细小内瘘口约登指数为-23.70%,曲线形面积为0.176;DCE-MRI对于细小瘘管显示约登指数为69.40%,曲线形面积为0.603,对于细小内瘘口约登指数为-4.80%,曲线形面积为0.201;瘘管造影+DCE-MRI对于细小瘘管显示约登指数为87.80%,曲线形面积为0.798,对于细小内瘘口约登指数为79.50%,曲线形面积为0.898。结论:钆剂瘘管造影与DCE-MRI联合使用检查对临床高位复杂型肛瘘的术前评估具有较高指导意义。
Objective:To diagnoze complex high anal fistula by combined use of MRI Ga fistula radiography and dynamic contrast enhanced MRI(DCE-MRI) and to explore its guiding significance for the diagnosis and treatment of high complex anal fistula. Methods:MRI confirmed 264 cases of high complex anal fistula complicated with small internal fistula,and uncleared branch fistula form December 10,2014 to December 10,2016. DCE-MRI check was firstly performed,than DCE-MRI and GA-DTPA 4 mL+ saline 16 mL in the fistula was soon performed through injection. Youden index and AUC test were performed to test the specificity and sensitivity of the results. Results:Fistulography+DCE-MRI clear displayed fistulography of high complex fistula,external fistula,branch fistula,and fistula T1WI;T2WI showed high signal. Abscess was irregular or horseshoe shaped,T1WI,slightly low signal,T2WI,high signal of fat suppression. The control results of surgery showed that fistulography+DCE-MRI obviously increased the diagnostic value for small fistula and small branch fistula. MRI scan for small fistula showed that Youden index was 31.60%,curve area was 0.576;MRI scan for small branch fistula showed that Youden index was -23.70%,and curve area was 0.176. DCE-MRI for small fistula showed that Youden index was 69.40% and curve area was 0.603;DCE-MRI for small branch fistula showed that Youden index was -4.80% and curve area was 0.201. Fistulography+DCE-MRI for small fistula showed that the Youden index was 87.80%,and curve area was 0.798;fistulography+DCE-MRI for small branch fistula showed that Youden index was 79.50% and curve area was 0.898. Conclusion:Fistulography+DCE-MRI have high clinical significance in the diagnosis and treatment of high complex anal fistula.
复杂型肛瘘磁共振成像钆剂瘘管造影动态增强磁共振成像
complex anal fistulamagnetic resonance imagingGa fistula radiographydynamiccontrast-enhanced magnetic resonance imaging
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