Objective：To evaluate the feasibility of observing visual center with resting-state functional magnetic resonance imaging （RS-fMRI） in patients with occipitalia tumor. Methods：Nineteen normal subjects and 8 patients with occipitalia tumor underwent RS-fMRI scanning and vision inspection before operation. All visual center networks in Brodmann area（BA） 17 and BA 18 were analyzed using independent component analysis（ICA）. The integrity and distribution of the visual center networks of the subjects were com－pared with the results of visual field examination. Results：In patient group，the strength and range of connection of visual center net－works in BA 17 and BA 18 were reduced to different degrees compared with those of normal control group and healthy side. The visual center function area showed displacement in 5 cases，the integrity of the visual center networks impaired in 6 cases，while the visual function connection in adjacent brain regions showed increase in 6 cases，the connection around tumor demonstrated increase in 4 cases. The integrity of the visual center networks of the 2 patients with visual field defect were damaged and visual function connection in adjacent brain regions showed increase. While the integrity of visual center network of 4 out of 6 patients with normal visual field were damaged，the visual function connection in adjacent brain regions and surrounding tumors showed increase and compensation. Conclusion：RS-fMRI could observe visual center networks of patients with occipitalia tumor，therefore，RS-fMRI scanning can help project operation or radiotherapy planning of the tumor and evaluate prognosis of the visual function.