Objective To analyze the clinical

ultrasound Sonogram features of orbital and adnexal lymphomas. Methods The clinical

ultrasound data of patients with orbital and adnexal lymphoma (79 cases) and orbital inflammatory pseudotumor (68 cases) from January

2017 to September

2021 were retrospectively analyzed. And statistically significant features were subjected to binary logistic regression analysis to establish a prediction model for distinguishing lymphoma from orbital inflammatory pseudotumor. The diagnostic accordance rate of ultrasound and MRI was also compared and analyzed. Results When comparing lymphoma with orbital inflammatory pseudotumor

there were significant differences in age

gender

lesion involves the number of quadrants

maximum tumor diameter

internal echogenicity

morphology

border

aspect ratio

internal strong echogenicity

"cast" tumor and "inverted triangle" tumor (P<0.05); as suggested by multivariate logistic regression

Logit (P) = -4.426 + 1.506 age ≥ 57.5 years + 1.473 male + 1.732 internal echogenicity (low/very low/nearly absent) + 1.888 casts + 1.356 strong internal dotted-line reticular echogenicity + 1.111 internal inhomogeneity. The area under the model curve was 0.913

and when judged as lymphoma by Logit (P) ≥ 0.556 and orbital inflammatory pseudotumor by Logit (P) < 0.556

the sensitivity was 82.9%

specificity 89.7%

and Youden index 0.720. The diagnostic accordance rate between ultrasound and MRI was 84.9% . Conclusion Orbital and adnexal lymphoma has characteristic ultrasound manifestations. The diagnostic model established by combining clinical and ultrasound features has clinical significance for the diagnosis and identifying of orbital lymphoma

and there is some agreement between ultrasound and MRI diagnosis.