ABSTRACT Objective To investigate the effect of hydraulic release of suprascapular nerve entrapment guided by muscle bone ultrasound and the risk factors of postoperative recurrence.Methods Methods 56 patients with suprascapular nerve entrapment diagnosed by clinical and EMG were collected. The suprascapular nerve was hydrolyzed under the guidance of muscle bone ultrasound as the study group (n = 29) and the suprascapular nerve block under the guidance of muscle bone ultrasound as the control group (n = 23). The changes of response latency of supraspinatus evoked potential (Lat)

visual analogue pain score (VAS) and Constant-Murley shoulder function score (CMS) were analyzed before treatment

4 weeks and 12 weeks after treatment in the two groups. Logistic regression analysis was used to analyze the risk factors of recurrence after treatment.Results There was no significant difference in VAS and CMS between the two groups at 4 weeks after treatment，but Lat in the study group was significantly shorter than that in the control group（P＜0.05）；while VAS，Lat and CMS in the study group were significantly lower than those in the control group 12 weeks after treatment（P＜0.05）.In the study group，VAS decreased，Lat shortened and CMS increased at 4 and 12 weeks after treatment（P＜0.05），while VAS decreased，Lat shortened and CMS increased at 12 weeks after treatment（P＜0.05）；In the control group，VAS decreased，Lat shortened and CMS increased at 4 and 12 weeks after treatment（P＜0.05）.12 weeks after treatment，the excellent and good rate in the study group was 93%，with 1 case of recurrence，while in the control group，the excellent and good rate was 70%，and 8 cases recurred.Multivariate regression analysis showed that age，sex and location had nothing to do with recurrence，but the method of treatment and course of disease were the risk factors of postoperative recurrence.Conclusion Ultrasound-guided hydraulic release of suprascapular nerve is effective in the treatment of suprascapular nerve entrapment and can reduce the risk of recurrence after treatment.