Objective To investigate the value of ultrasound and multi-slice spiral CT in the differential diagnosis of renal eosinophilic adenoma and chromophobe cell carcinoma. Methods The clinical data of 45 cases of chromophobe cell carcinoma and 30 cases of renal eosinophilic adenoma confirmed by surgery and pathology were retrospectively analyzed. The study period was from February 2017 to October 2020. Both ultrasound and multi-slice spiral CT were performed. Compare the CT signs of renal eosinophilic adenoma and chromophobe cell carcinoma

observe the LKR value

△AT

△TTP

△PI of the plain scan

cortical phase

parenchymal phase

and excretion phase

and analyze the LKR value of each phase

ROC curve of △AT

△TTP

△PI

combined diagnosis. Results Routine ultrasound findings: renal eosinophilic adenoma and chromophobe cell carcinoma had no significant difference in the nature

echo

morphology and boundary of the lesion (P>0.05).Contrast-enhanced ultrasound findings: There was no statistically significant difference between renal eosinophil adenoma and chromophobe cell carcinoma in the enhancement mode and the decrease mode (P>0.05);Renal eosinophilic adenoma and chromophobe cell carcinoma had statistical significance in peak intensity

enhancement uniformity

pseudocapsule

△AT

△TTP

and △PI (P＜0.05).CT analysis showed that renal eosinophilic adenoma and chromophobe cell carcinoma were statistically significant in the comparison of star-shaped scars and uniform enhancement (P＜0.05); renal eosinophilic adenoma and chromophobe cell carcinoma were in cystic change There was no statistically significant difference in the proportions of

necrosis

calcification

capsule

spoke-like enhancement

segmental enhancement reversal

and bleeding (P>0.05).There was no significant difference in the LKR values of renal eosinophil adenoma and renal chromophobe cell carcinoma (P>0.05); the LKR values of renal eosinophil adenoma in cortical

parenchymal and excretory phases were higher than those in renal chromophobe cell carcinoma Chromophobe cell carcinoma (all P＜0.05).ROC curve analysis showed that the LKR AUC values of plain scan

cortical phase

parenchymal phase

and excretion phase in multi-slice spiral CT were (0.525

0.931

0.800

0.850

P<0.05); △AT

△TTP

△PI The AUC values were (0.990

0.673

0.909

P<0.05); the AUC value of the combined diagnosis was (0.955

P<0.05). Conclusion Both ultrasound and multi-slice spiral CT have high predictive value in the diagnosis of chromophobe cell carcinoma

especially contrast-enhanced ultrasound

which can provide important information for the differentiation of renal eosinophilic adenoma and chromophobe cell carcinoma

but in order to avoid missed diagnosis If it occurs

it is recommended that the above two methods be combined clinically for diagnosis.