多模态超声诊断技术诊断桥本氏甲状腺炎合并良恶性结节的价值研究

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多模态超声诊断技术诊断桥本氏甲状腺炎合并良恶性结节的价值研究

临床研究 | 更新时间：2023-10-09

- 多模态超声诊断技术诊断桥本氏甲状腺炎合并良恶性结节的价值研究
- Diagnostic value of multimodal ultrasonography in benign and malignant thyroid nodules
- 临床超声医学杂志 2020年22卷第10期
- 作者机构：
  
  成都市龙泉驿区第一人民医院
- 作者简介：
- 基金信息：
  
  项目基金：四川省成都市卫生局科学研究基金（2016020）
- DOI：
  中图分类号：
- 纸质出版日期：2020，
  
  网络出版日期：2020-10-28，
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罗雪. 多模态超声诊断技术诊断桥本氏甲状腺炎合并良恶性结节的价值研究[J]. 临床超声医学杂志, 2020,22(10).

Luo Xue. Diagnostic value of multimodal ultrasonography in benign and malignant thyroid nodules[J]. Journal of Clinical Ultrasound in Medicine, 2020,22(10).
罗雪. 多模态超声诊断技术诊断桥本氏甲状腺炎合并良恶性结节的价值研究[J]. 临床超声医学杂志, 2020,22(10). DOI：

Luo Xue. Diagnostic value of multimodal ultrasonography in benign and malignant thyroid nodules[J]. Journal of Clinical Ultrasound in Medicine, 2020,22(10). DOI：

摘要

摘要目的评价单独二维超声、弹性成像、超声造影及其联合检查在桥本氏甲状腺炎合并良恶性结节中的诊断价值。方法对44例桥本氏甲状腺炎患者的54个结节分别行二维超声、弹性成像及超声造影检查，将超声诊断结果与病理结果对照并分析，计算并比较单独二维超声、弹性成像、超声造影及三者联合应用对桥本氏甲状腺炎合并良恶性结节的诊断效能。结果以TI-RADS 4、5类为二维超声诊断恶性结节的标准，二维超声的诊断敏感性、特异性及准确率分别为50.0%、82.5%、74.0%；以剪切波弹性成像测得结节杨氏模量值≥46.1 kPa作为恶性结节的预测指标，弹性成像的诊断敏感性、特异性及准确率分别为57.1%、85.0%、77.7%；以不均匀性低增强为恶性结节的诊断标准，超声造影的诊断敏感性、特异性及准确率分别为64.3%、80.0%、75.9%；三者联合检查的诊断敏感性、特异性及准确率分别为85.7%、95.0%、92.5%。三者联合检查的准确性高于单一检查，差异均有统计学意义（均P＜0.05）。结论多模态（二维超声、弹性成像、超声造影）超声联合检查较单一检查对桥本氏甲状腺炎合并良恶性结节更有诊断价值，值得进一步推广应用。

Abstract

ABSTRACT Objective To evaluate the diagnostic value of single two-dimensional ultrasound

elastography

contrast-enhanced ultrasound and their combined examinations in Hashimoto’s thyroiditis with benign and malignant nodules.Methods Two-dimensional ultrasound

elastography

and contrast-enhanced ultrasound were performed on 54 nodules in 44 patients with Hashimoto’s thyroiditis. The ultrasound diagnosis results were compared with the pathological results and analyzed

and the two-dimensional ultrasound

elastography

and ultrasound were calculated and compared. The diagnostic efficiency of angiography and the combination of the three for Hashimoto's thyroiditis with benign and malignant nodules.Results Using TI-RADS 4 and 5 as the criteria for the diagnosis of malignant nodules by two-dimensional ultrasound

the sensitivity

specificity and accuracy of two-dimensional ultrasound are 50.0%

82.5%

and 74.0%

respectively; measured by shear wave elastography The Young’s modulus value of nodule ≥ 46.1 kPa is used as a predictor of malignant nodules. The diagnostic sensitivity

specificity and accuracy of elastography are 57.1%

85.0%

and 77.7%

respectively. The low heterogeneity enhancement is The diagnostic criteria for malignant nodules

the diagnostic sensitivity

specificity

and accuracy of contrast-enhanced ultrasound were 64.3%

80.0%

and 75.9%

respectively; the diagnostic sensitivity

specificity

and accuracy of the three combined examinations were 85.7%

95.0

respectively %

92.5%. The accuracy of the combined inspection of the three was higher than that of the single inspection

and the differences were all statistically significant (all P<0.05).Conclusion TMultimodal (two-dimensional ultrasound

elastography

contrast-enhanced ultrasound) combined ultrasound examination is more valuable than a single examination in the diagnosis of Hashimoto's thyroiditis with benign and malignant nodules

and it is worthy of further promotion and application.

关键词

超声检查桥本氏甲状腺炎甲状腺结节良恶性

Keywords

UltrasonographyHashimoto's thyroiditisThyroid nodulesBenign and malignant

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