Objective To evaluate the degree of hepatic fibrosis and steatosis and their correlation in patients with type 2 diabetic nephropathy (DN) by FibroTouch technique. Methods Ninety patients with type 2 diabetic nephropathy were enrolled and divided into three groups according to the level of estimate glomerular filtration rate (eGFR): eGFR≥90ml ?min-1 (1.73m2)-1 as group A (n=30); 60ml ?min-1 (1.73m2)-1≤ eGFR<90ml ?min-1 (1.73m2)-1 as group B (n=30) and eGFR<60 ml ?min-1 (1.73m2)-1 as group C (n=30). Meanwhile

30 healthy volunteers were enrolled as normal control group. The fat attenuation value (db/m) and the liver stiffness value (Kpa) were obtained by FibroTouch technique. Results The fat attenuation values and the liver stiffness values of the group A

B and C were significantly higher than that of the control group (all P<0.05). The fat attenuation value (db/m) and the liver stiffness value (Kpa) of the group B and C were higher than that of the group A (all P<0.05).And The fat attenuation value (db/m) and the liver stiffness value (Kpa) of the group C was higher than that of the group B (P<0.05). The fat attenuation value was positively correlated wirh the liver stiffness value(r=0.733

P<0.01). Conclusion The degree of hepatic steatosis and fibrosis of DN patients can be evaluated accurately and non-invasively by FibroTouch technique with an important clinical value.