Kimura disease is a rare benign and chronic infiltrative disease. The etiology is not clear. It may be related to immune disorders

allergic reactions

non-specific infections and other related [1]. The clinical manifestations are mainly chronic pain prone subcutaneous soft tissue tumors

which are common in salivary glands. The disease can occur at any age and the incidence rate of male is far higher than that of women. Kimura disease has a benign course. According to previous studies

the recurrence rate is high. Laboratory examination showed that the peripheral blood eosinophil count increased and the serum IgE level increased [2]. The specific ultrasonic manifestations of this case are: hypoechoic lesions in bilateral submandibular glands

with multiple small flake hypoechoic intervals mixed with "grid" hyperechoic

rich blood flow signals

unclear boundary between skin and medulla of lymph nodes in and around the glands

and "portal" blood flow signals. It is mainly differentiated from hemangioma in soft tissue. The ultrasonic manifestations of hemangioma are spindle

round or ovoid tumors in soft tissue

with clear or unclear boundary

uneven internal echo

mostly low echo

typical honeycomb structure can be seen

rich blood flow signals can be detected

the blood flow signals increase after the pressure of the probe is loosened

and there is no enlargement of surrounding lymph nodes. However

after the Kimura disease probe was pressurized

the mass deformation was not obvious

and the blood flow signal changed little

which can be distinguished from hemangioma. It is difficult to make a definite diagnosis of Kimura disease before operation. Ultrasound is the first choice for the diagnosis of Kimura disease and postoperative follow-up observation.