Contrast echocardiography is a new cardiovascular angiography technology

which combines echocardiography and contrast acoustic technique

including right and left heart contrast echocardiography. Left heart contrast echocardiography is now vividly used in clinic

including left ventricular opacification and myocardial contrast echocardiography. This technology enhances the visualization of cardiac and vascular cavity

thus improving the display effect of cardiac chamber and myocardium

and can also intuitively prompt heart perfusion. The European Association of Cardiovascular Imaging and the American Society of Echocardiography were both published related guideline updates in 2017 and 2018. Clinical applications and guideline recommendations of left heart contrast echocardiography were reviewed in this paper.