Tuberculosis (TB) is one of the main causes of infectious diseases-related death in the whole world

which spreads worldwide and can invade widely all organs of the body

which poses a great threat to human health. Its occurrence and development are affected by many factors. Besides traditional environmental factors

genetic polymorphism has been paid more and more attention. Studies with interferon-γ (IFNG)

P2X7

vitamin D receptor (VDR) and other gene polymorphisms have been found to be significantly associated with the susceptibility of tuberculosis

and related research is bound to bring new ideas for tuberculosis prevention and treatment. In this paper

we systematically summarizes the genes related to the genetic susceptibility of tuberculosis

providing reference for tuberculosis prevention in the future.