Aspirin is a cyclooxygenase inhibitor with anti-inflammatory and anti-platelet properties. As indicated by several national guidelines

low-dose aspirin (LDA) use in obstetrics and assisted reproduction has recently increased

particularly for the prevention of preeclampsia. At the same time

LDA can effectively improve the placental hypoperfusion by inhibiting the activity of cyclooxyge-nase to exert the effect of anti-platelet aggregation

and its indications for fetal growth restriction

preterm birth

obstetric antiphospholipid syndrome

assisted reproductive technology

and other conditions have been gradually expanded. This article reviews the recommendations and research progress of various guidelines on the application of low-dose aspirin in obstetrics and assisted reproduction.