Abstract: ObjectiveTo compare the treatment effect of autologous blister skin grafting with ReCell autologous chromocyte grafting on cicatricial depigmentation caused by deep burn.MethodsThirty-four patients with cicatricial depigmentation caused by deep burn who were admitted into hospital from May 2012 to February 2015 were included in this study.The total 61 depigmentation areas were randomly divided into two groups:32 areas from 18 patients were treated with autologous blister skin grafting

and the other 29 areas from 16 patients were treated with ReCell autologous chromocyte grafting.In the autologous blister skin grafting treated group

epidermis from the depigmentation area was removed by grinding with a BY-II AM type epidermal graft vitiligo treatment equipment.Then the autologous blister skin was harvested with the suction blistering method and grafted onto the wound of depigmentation area.In the ReCell autologous chromocyte grafting treated group

split-thickness skin flap was harvested by electric dermatome.Then the donor skin was processed into chromocyte suspension with the ReCell assay kit and evenly sprayed onto the depigmentation areas.The wound healing time and the pigment recovery 3 months after surgery were observed.ResultsThe wound healing time of autologous blister skin grafting treated group was significantly shorter than that of ReCell autologous chromocyte grafting treated group (P<0.05).The effective rate of pigment recovery 3 months after surgery in autologous blister skin grafting treated group was markedly higher than that of ReCell autologous chromocyte grafting treated group(P<0.05).ConclusionThe autologous epidermal grafting treatment using grinding and suction blistering method is simple and easy to perform

markedly effective

with no suture scar and low surgical risk

thus serving as a promising and ideal therapeutic method for burn scar depigmentation.