Objective To investigate the effects of early tracheotomy on patients with pulmonary infection after severe craniocerebral injury

and to explore the changes in biochemical factors. Methods A total of 288 patients with severe craniocerebral injury who were treated in our intensive care unit from March 2017 to August 2018 were enrolled

and they were divided into two groups. Patients underwent tracheotomy within 24 hours after craniocerebral injury were included in the observation group

and patients underwent tracheotomy 24 hours after craniocerebral injury were included in the control group. The pulmonary infection incidence

infection control rate

infection control time

changes of biochemical factors creactive protein (CRP) and procalcitonin (PTC) were compared between the two groups. Results The pulmonary infection incidence and average infection control time in the observation group were lower than the control group

but the infection control rate in the observation group was higher than that of the control group

and the difference between the two groups was statistically significant (P<0.05).The CRP and PCT at the 1st

3rd

7th

and 10th day after surgery in the two groups were significantly increased compared to those before the surgery

and the difference between the two groups was statistically significant (P<0.05). At the 7th and 10th day after surgery

the PCT of the observation group was significantly lower than that of the control group with statistically significant difference (P<0.05). Conclusion Early tracheotomy for patients with severe craniocerebral injury can reduce the rate of pulmonary infection.