Objective To investigate the application and advantages of alternative vascular hemihepatic occlusion in anatomic mesohepatectomy.Methods The clinical data of 57 patients with liver cancer who underwent operation in hepatobiliary surgery of Fuzhou general hospital from January 2014 to December 2017 were retrospectively analyzed.According to the surgery method

the patients were divided into observation group and control group

34 cases in observation group were performed anatomic mesohepatectomy with alternative hemihepatic occlusion

23 cases in control group were treated with nonanatomical liver lobectomy.The clinical effect of two groups were compared.ResultsThe observation group was significantly better than the control group in terms of operation time

intraoperative blood loss

length of hospital stay

hospitalization costs

ALB at 1

3

5 days after surgery

ALT and AST at 1

3

5

7 days after surgery

the differences were significant(P<0.05).There was no perioperative deaths in the two groups.Conclusion Applied alternative hemihepatic vascular occlusion in anatomic mesohepatectomy can achieve good short-term curative effect and high safety.