Objective To investigate the efficacy of Ilizarov technique in treatment of Gustilo type Ⅲ B and C of large tibia bone defect combined with soft tissue defect.Methods Thirty cases with large tibia bone defect combined with soft tissue defect in our hospital from January 2016 to December 2018 were selected including 25 cases with type Ⅲ B and 5 cases with type Ⅲ C

who were all open tibia fractures and treated with Ilizarov technique.Results All patients were followed up for 10 to 18 months with an average of 15 months.The bone defects were reconstructed

the difference between the length of the affected limb and the healthy side was less than 2 cm.The fracture was healed and the wound was closed. One case was with paralysis of common peroneal nerve and recoveried after 3 months.Twentytwo cases recovered without extra surgery

five cases restored with skin graft and three cases covered the wound by rotating skin flap.Conclusion Ilizarov technique is one of effective ways to treat Gustilo Ⅲ type B and type C of large defect combined with soft tissue defect.