Objective To predict the occurrence risk of MVI through the patient′s regular examination and EOBMRI imaging examination

and to establish a prediction model for clinical work. Methods The clinical data of 157 patients with single HCC admitted to our hospital were retrospectively analyzed. The preoperative EOBMR imaging information including tumor diameter

shape(margin)

peritumoral hyperintensity in arterial phase

peritumoral hypointense in hepatobiliary phase

capsule integrity and diffusion weighted magnetic resonance imaging(DWI) were analyzed.The patients were divided into two groups according to the tumor diameter

one group was equal to or greater than 3 cm in diameter and the other group was less than 3 cm in diameter

and the risk factors of MVI between two groups were statistically analyzed. ResultsMultivariate logistic analysis indicated that the tumor diameter (P=0.035)

the peritumoral hypointense in hepatobiliary phase(P=0.026)

and the capsule integrity(P<0.001) were correlated with the occurrence of MVI.The model obtained verifies that the sensitivity and specificity of MVI were 77.3 % and 85.1 % respectively.After grouping

multivariate analysis in the group with tumor diameter less than 3 cm suggested that the peritumoral hypointense in hepatobiliary phase(P=0.016) was an independent risk factor for the occurrence of MVI;While multivariate analysis in the group with tumor diameter equal to or greater than 3 cm suggested that the hepatitis B history (P=0.024)

capsule integrity (P<0.001)

and peritumoral hypointense(P=0.049) were independent risk factors for the occurrence of MVI. Conclusion Regardless of tumor diameter

peritumoral hypointense in hepatobiliary phase

and capsule integrity are independent risk factors for MVI occurrence.When the diameter of tumor is less than 3 cm

the peritumoral hypointense in hepatobiliary phase can be used as a predictor of MVI

when the diameter of tumor is equal to or greater than 3 cm

the hepatitis B history

capsule integrity and the peritumoral hypointense in hepatobiliary phase can be used as predictors of MVI.