Objective To explore the value of threedimensional texture and shape features of magnetic resonance imaging (MRI) in the differential diagnosis of vestibular schwannoma and cerebellopontine angle meningioma.Methods The data of 35 patients were retrospectively analyzed

of whom 19 patients with vestibular schwannoma and 16 patients with cerebellopontine angle meningioma.Threedimensional texture and shape analysis based on MRI was used to evaluate the detectable differences between the two malignancies.Single factor independent t test and receiver operating characteristic(ROC) curve were used to analyze and calculate the corresponding sensitivity

specificity

accuracy and area under the curve(AUC).Results The characteristics of mean

heterogeneity

skewness and kurtosis were extracted from T1 images

the results showed that the heterogeneity and skewness had high identified ability.The best predictive factor was heterogeneity（AUC=0.87）

the skewness followed closely（AUC=0.72）. The sensitivity and specificity of inhomogeneity were 0.84 and 0.75

and the skewness were 0.74 and 0.63

respectively. Conclusion Texture analysis of inhomogeneity and skewness parameters combined with conventional MRI plain scan manifestations has certain clinical application value for the differentiation of vestibular schwannoma and cerebellopontine angle meningioma.