
浏览全部资源
扫码关注微信
目的:建立测定酒石酸唑吡坦原料药中痕量钯的方法。方法:采用石墨炉原子吸收光谱法,样品用1%盐酸溶液溶解后直接测定。采用横向平台石墨管,检测波长为244.79 nm,光谱带宽为0.2 nm,空心阴极灯工作电流强度为6 mA,扣背景方式为塞曼效应,测量模式为峰高,进样量为20 μl。结果:钯的检测质量浓度线性范围为0~100 ng/ml(r=0.999 0);精密度、重复性试验的RSD≤2.0%;加样回收率为97.78%~103.07%,RSD=1.6%(n=9);检测限为1.48 ng/ml。结论:该方法操作简便、迅速,具有良好的精密度和准确度,可用于酒石酸唑吡坦原料药中痕量钯的测定。
OBJECTIVE:To establish a method for determination of trace platinum in zolpidem tartrate. METHODS: Graphite furnace atomic absorption spectrometry (GFAAS) was adopted for direct determination after dissolving sample in 1% Hydrochloric acid solution. Horizontal platform graphite tube was performed with detection wavelength of 244.79 nm, slit width of 0.2 nm and current intensity of hollow cathode lamp of 6 mA. The mode of background correction was zeeman effect, the peak height was used as measurement pattern, and the injection volume was 20 μl. RESULTS: The linear range of platinum was 0-100 ng/ml (r=0.999 0); RSDs of precision and reproducibility tests were no more than 2.0%; recovery was 97.78%-103.07% (RSD=1.6%,n=9); the detection limit was 1.48 ng/ml. CONCLUSIONS: This method is simple and rapid with good precision and accuracy, and can be applied for the determination of trace platinum in zolpidem tartrate.
酒石酸唑吡坦钯石墨炉原子吸收光谱法
Zolpidem tartratePlatinumGraphite furnace atomic absorption spectrometry
0
浏览量
5
下载量
0
CSCD
关联资源
相关文章
相关作者
相关机构
京公网安备11010802024621