Objective To investigate the effect of invasion depth and extent of adenomyosis on pregnancy abortion rate

in order to provide a reference for clinical treatment. Methods A total of 102 patients with adenomyosis who intended for pregnancies and were admitted to the Shenyang Women’s and Children’s Hospital from January 2018 to January 2021 were selected as the study subjects. AⅡ patients underwent color Doppler ultrasonography and the depth and extent of adenomyosis invasion were identified. According to the depth of lesion invasion

the patients were divided into BⅠ and BⅡ grades. According to the extent of lesion invasion

the patients were divided into AⅠ

AⅡ

and AⅢ grades. The abortion rate of pregnancy was compared between patients with varying depths and extent of lesion invasion. The effect of the extent and depth of lesion invasion on the abortion rate was analyzed by the logistic regression model. Results Among 102 patients with adenomyosis

25（24.51%） had AⅠ

54（52.94%） AⅡ

and 23（22.55%） AⅢ. Among 102 patients with adenomyosis

62（60.78%） had BⅠ and 40（39.22%） BⅡ. There were significant differences in the abortion rate between patients with different depths and extents of lesion invasion（P <0.05）. Logistic regression analysis showed that the extent and depth of lesion invasion were risk factors for pregnancy abortion in adenomyosis patients（P<0.05）. Conclusion An influencing mechanism between adenomyosis and abortion was observed. The abortion rate of pregnancy increases with the aggravation of the invasion of adenomyosis. Color Doppler ultrasonography should be performed in adenomyosis patients with pregnancy desire to identify the depth and extent of invasion. Early intervention should be taken for the high-risk abortion population to reduce the abortion rate of patients.